The effects of cold temperature were studied nearly 300 years ago by Robert
Boyle, who published a monograph entitled New Experiments & Observations
Touching Cold. Since then numerous studies have been published on the subject
of cryobiology. In recent years, detailed and comprehensive works about cryobio-
logy and cryosurgery have been described by many investigators, among them
Parkes, Rowbotham et al, Meryman, Hankinson, Smith, Von Leden and Cahan.
This work for comparative studies on effects of skin cryodestruction was attempt
to investigate a difference beta,~en Frigitronics and walnuts instruments for the
_--effects--of-skin cryodestruction..
|